DAPT

Purity: ≥98%

Synonym(s): GSI-IX; GSI IX; γ-Secretase Inhibitor IX; LY-374973; N-[N-(3, 5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester; (3, 5-Difluorophenylacetyl)-L-alanyl-L-2-phenylglycine tert-Butyl Ester; (3, 5-Difluorophenylacetyl)-Ala-Phg-OtBu

Formula: C23H26F2N2O4 Molecular Weight: 432.46

CAS Number: 208255-80-5 MDL Number: MFCD04974585 PubChem CID: 5311272

Properties

Shelf life: 730 days

Solubility: Soluble in DMSO (15 mg/mL), ethanol (~1 mg/mL), dichloromethane, DMF (~25 mg/mL), and 1: 9 solution of DMF: PBS(pH 7.2) (~0.1 mg/mL).

Sensitivity: Heat sensitive

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Melting point:

InChl: InChI=1S/C23H26F2N2O4/c1-14(26-19(28)12-15-10-17(24)13-18(25)11-15)21(29)27-20(16-8-6-5-7-9-16)22(30)31-23(2, 3)4/h5-11, 13-14, 20H, 12H2, 1-4H3, (H, 26, 28)(H, 27, 29)/t14-, 20-/m0/s1

Safety Information

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Precautionary Statements:

WGK: 3

Storage: Store at 2-8°C; Argon charged

Personal Protective Equipment: Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter