Entinostat (MS-275)

Purity: ≥98%

Synonym(s): MS-275; SNDX-275; MS 275; SNDX 275; A HDAC1 and HDAC3 inhibitor; 3-pyridinylmethyl [[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]carbamate; N-(2-Aminophenyl)-4-[N-(pyridine-3ylmethoxycarbonyl)aminomethyl]benzamide

Formula: C21H20N4O3 Molecular Weight: 376.41

CAS Number: 209783-80-2 MDL Number: MFCD03453552 PubChem CID: 4261

Properties

Shelf life: 730 days

Solubility: Soluble in methanol, DMSO (~30 mg/ml), DMF (~30 mg/ml), ethanol (~2 mg/ml), 1: 1 solution of DMSO: PBS(PH7.2) (~0.5 mg/ml), and water (<1 mg/ml) at 25 °C. Sensitivity: Air Sensitive, Heat Sensitive Boiling point: Melting point: 160 °C InChl: InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H, 13-14, 22H2, (H, 24, 27)(H, 25, 26)

Safety Information

Pictograms: GHS06; GHS08; GHS07

Signal Word: Danger

Hazard Statements: H315; H319; H335; H301; H360

Precautionary Statements: P261; P305+P351+P338; P280; P302+P352; P321; P405; P501; P264; P271; P270; P304+P340; P403+P233; P362+P364; P330; P203; P264+P265; P301+P316; P318; P337+P317; P332+P317; P319

WGK: 3

Storage: Store at -20°C

Personal Protective Equipment: